Nouns ending in -tion are feminine.
The suffix forms abstract nouns of action or state.
Is interprétation masculine or feminine?
l'interprétation
The rule behind it
99.8% of -tion nouns are feminine
In context
Cette phrase est susceptible d'une autre interprétation.
This sentence may be interpreted another way.
L'interprétation de la jeune violoniste était géniale.
The performance by the young violinist was awesome.
La question ne permet qu'une seule interprétation.
The question only allows one interpretation.