Nouns ending in -ie are usually feminine.
The suffix often names an abstract quality, an activity, or a discipline.
Is pénurie masculine or feminine?
lapénurie
The rule behind it
95.7% of -ie nouns are feminine
In context
La sécheresse conduisit à une pénurie de nourriture.
The drought led to an insufficiency of food.
Il y a pénurie d'encre d'imprimerie.
Printing ink is in short supply.
Il y a une grave pénurie d'eau.
There is an acute shortage of water.